With Blogger, you can take advantage of a feature called "Comment Moderation." For example, I currently have it set so that I can approve or reject any comments made on posts older than seven days old. 99% of these comments are spam, and it's a good way to keep spam out while making the commenting process go as smoothly as possible for you, the real-life human commenter.
I just saw the following in my Comment Moderation screen (read it carefully). What would you do?
(I rejected it. That poor soul...)